Itoje, who has become one of England's key players and helped them win the 2017 Six Nations title, suffered a fractured jaw in a collision with England team mate Mike Brown in Saracens' Premiership match against Harlequins on Dec. 3.
It was feared his recovery could take more than two months, which would have ruled him out of the start of the Six Nations, but McCall, the Saracens' director of rugby, said that timeframe had shortened.
"Maro Itoje will probably be back in three or four weeks' time -- maximum six weeks -- and he's had a week and a half already," McCall told the club website on Thursday.
News that makes sense
Your trusted source for staying up-to-date with the world around you. Get free daily news updates and analysis, straight to your inbox.
The time frame should see Itoje -- who, ironically, had his playing time managed during England's recent tests -- back in action for his club ahead of the Italy game.
The BBC reported McCall as saying that Itoje, who had two plates inserted in his face, had been told by his specialist that he faced a maximum of four weeks' rehabilitation.
(Reporting by Neville Dalton; Editing by Greg Stutchbury)
