Lamela, who has 23 caps, last played for the national side against Venezuela in a World Cup qualifier in 2016 but missed much of last season and the Russia World Cup with a hip injury.
Interim coach Lionel Scaloni also gave a first call up to Racing's 20-year-old attacking midfielder Matias Zaracho.
There was no place for Lionel Messi, who announced he was taking a sabbatical from international football after Argentina's disappointing performance in Russia, where they won only one game and were knocked out by France in the last 16.
Argentina will play Mexico in Cordoba on Nov. 16 and then again in Mendoza four days later.
(Reporting by Andrew Downie; Editing by Toby Davis)