Argentina have been forced into a late change for their Rugby Championship clash with Australia when midfield regular Jeronimo de la Fuente failed a fitness test on Friday.
De La Fuente, who has started in every Pumas Test this year, injured his left leg in training and has been replaced by Santiago Gonzalez Iglesias.
Saturday's game will be his first start in almost a year.
Three-time rugby World Cup back Juan Martin Hernandez comes onto the reserves bench for a match in which the Pumas are out to redeem themselves.
They are at risk of failing to earn a competition point for the first time since joining the competition in 2012.
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"We are failing to carry out the game plan," flanker Pablo Matera said.
"The system is not failing, it is us players who are failing."
Matera said they remain determined to beat the Wallabies, as they did in the same Malvinas Argentinas Stadium in 2014.
"If we beat Australia, we can finish the championship by beating a top team," he said.
"To beat Italy in November will not give us anything."
ARGENTINA: Joaquin Tuculet, Matias Moroni, Matias Orlando, Santiago Gonzalez Iglesias, Emiliano Boffelli, Nicolas Sanchez, Martin Landajoi, Javier Ortega, Tomas Lezana, Pablo Matera, Matias Alemanno, Marcos Kremeri, Nahuel Tetaz Chaparro, Agustin Creevy (capt), Lucas Noguera. Reserves: Julian Montoya, Santiago Garcia Botta, Enrique Pieretto, Benjamin Macome, Leonardo Senatore, Gonzalo Bertranou, Juan Martin Hernandez, Santiago Cordero.
