Kawhi Leonard scored a season-high 37 points, Pascal Siakam added a career-high 26 and Toronto overcame a 51-point performance from Kevin Durant to beat Golden State 131-128 in overtime on Thursday night.
The victory extended the red-hot Raptors' winning streak to seven.
Kyle Lowry had 10 points and 12 assists, Serge Ibaka scored 20 points and Danny Green had 13 as the Raptors snapped an eight-game losing streak against Golden State and won a contest billed as a potential NBA Finals preview.
Toronto improved their league-leading record to 19-4.
Durant scored 40 or more in three straight games for the first time, finishing with his highest total of the season. He also had 11 rebounds and six assists.
News that makes sense
Your trusted source for staying up-to-date with the world around you. Get free daily news updates and analysis, straight to your inbox.
Klay Thompson scored 23 points and Jonas Jerebko had 16 of his 20 in the fourth quarter and overtime, but Golden State lost to Toronto for the first time since March 2014.
In Los Angeles, LeBron James scored 12 of his 38 points in the final five minutes as the Lakers rebounded from their first back-to-back losses in a month with a 104-96 victory over the Indiana Pacers.
Brandon Ingram scored 14 points and Josh Hart added 13 for the Lakers, who blew an early 24-point lead before James carried them down the stretch to their 10th win in 14 games.
Victor Oladipo sat out his sixth straight game for Indiana with a sore right knee. Domantas Sabonis stepped up with 20 points and 15 rebounds but the Pacers lost for the first time in three stops on their four-game West Coast trip.
The Los Angeles Clippers beat the Kings 133-121 thanks to 28 points from Tobias Harris and 24 from Montrezl Harrell.
The Clippers haven't lost in Sacramento since March 19, 2013 - extending their streak to 12 games.
Bogdan Bogdanovic scored a career-high 26 for the Kings while Marvin Bagley III added 18 points and 10 rebounds.
