North had been sent by Wales back to his club Northampton last week to get some game time. In his first appearance in a month following a knee injury, he made an impressive showing, scoring a try in Friday's 36-10 win over Harlequins in the Anglo-Welsh Cup.
Williams, who plies his trade for Saracens, has not played much since suffering an abdominal injury last year.
Wales began their Six Nations campaign with a 34-7 home triumph over Scotland in Cardiff on Saturday, despite a myriad of injuries.
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They will take on an England team who easily beat Italy in Rome as they seek to win a third successive championship.
(Reporting by Mark Gleeson; Editing by Christian Radnedge)
