Liverpool manager Juergen Klopp, who was already without forwards Danny Ings and Daniel Sturridge due to injury, has only Christian Benteke fit among his senior strikers.
The 20-year-old Origi, who has scored four goals in 16 appearances this season, is set to miss at least five league matches, the FA Cup third-round replay against Exeter City and the second leg of the League Cup semi-final against Stoke City.
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(Reporting by Shravanth Vijayakumar in Bengaluru, editing by Ed Osmond)
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