The Australian duo, who were bidding for their first grand slam title together, struggled for the majority of the hour-long contest after their serve was broken three times in each set.
Mattek-Sands, however, praised her opponents, who had dropped just one set on their way to the final.
"You guys have done a great job and you're an awesome team,” the 32-year-old said. "I’m sure we're gonna be facing you again soon."
The Australian pair reached three grand slam finals together in 2013 without taking home the trophy and were unable to end their long wait in Paris, while Dellacqua's overall record in women's doubles finals is 0-7.
(Reporting by Hardik Vyas in Bengaluru; Editing by Toby Davis)
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