"We are going to close the path to the money coming from kidnapping, extortion, drug trafficking or any other crime," Calderon said at a public event in which he signed the proposals and sent them to Congress for approval.
The crackdown includes limiting cash transactions to some 7,600 dollars at a time in the purchase of vehicles and jewelry, among other things. The big-ticket items can be bought with a check or a credit card.
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The government will also tighten control over real estate companies, companies that issue credit cards, companies in the security business, jewelers, attorneys and accountants, among others.
Mexico will also increase collaboration with foreign police specializing in financial crimes, Calderon said.
Mexican officials estimate that the country obtains some 10 billion dollars in drug proceeds each year.
In mid June the government limited bank cash transactions to 4,000 dollars a month per person, and 7,000 dollars a month per company.
Calderon has made cracking down on illegal drug cartels a priority of his administration.
More than 28,000 people have been killed in drug-related violence since December 2006, when Calderon launched a nationwide crackdown against narcotraffickers.

