NSW's roads minister is "concerned and disturbed" by the number of heavy vehicle crashes on state roads, with six trucks involved in deadly crashes within 24 hours.
Two people were killed on Tuesday when a B-Double truck ploughed into cars stopped at roadworks, injuring at least 10 others near Dubbo.
The crash came less than a day after two separate fatal crashes involving trucks on NSW roads.
Roads Minister Melinda Pavey described the latest truck crash as "an absolute horror".
"I am just so concerned and disturbed about the level of accidents involving heavy vehicles in NSW at the moment," Ms Pavey told ABC News.
"We've had six heavy vehicles involved in accidents in the past 24 hours which are going to destroy lives, destroy families."
Meanwhile, one truck driver was killed and one other injured in a fiery crash south of Newcastle involving three heavy vehicles on Monday.
Two other truck drivers were killed near Grafton when their trucks collided on the same day.
Ms Pavey said she was worried about the 45 per cent increase in heavy vehicle accidents on the state's roads between 2016 and 2017, adding that increased activity on NSW roads was not enough to explain the jump.
She said speed was still the leading contributor in fatal crashes on NSW roads, while fatigue, drugs and alcohol also played significant roles.
NSW Police Superintendent Peter McKenna urged drivers to rest when they needed to and not use drugs or drink alcohol when driving.
"We need people to adhere to the messages police are putting forward about road safety," he told reporters near Dubbo.
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