Ben Roethlisberger has thrown for 300 yards and four touchdowns for Pittsburgh who have pulled away from Tennessee in a 40-17 NFL victory.
Running the no-huddle offence extensively for the first time all season, Roethlisberger completed 30 of 45 passes on Thursday night to help the Steelers (8-2) to win their fifth straight.
Antonio Brown caught 10 passes for 144 yards and three touchdowns, including an acrobatic grab in the back of the end zone. He he pinned the ball to his helmet before bringing it in to put Pittsburgh up by 20 points in the fourth quarter.
Marcus Mariota ran for a touchdown and threw for another but also was picked off four times, as the Titans' (6-4) four-game winning streak come to a crashing halt.
Mariota finished 22 of 33 for 306 yards but was under pressure much of the night, absorbing five sacks and rarely finding room to move outside the pocket.
Still, Tennessee appeared to be in it when Mariota hit Rishard Matthews with a 75-yard touchdown pass on the first play of the second half to get to 16-14 but Pittsburgh's long-sputtering offence finally came to life.
Roethlisberger dropped some very not-subtle hints that he wanted the freedom provided by the no-huddle after the Steelers used it to pick the Colts apart during the winning drive last Sunday in Indianapolis.
Next up, the Titans visit Indianapolis on November 26, while the Steelers welcome the Green Bay Packers on the same day.
