The 19-year-old Benfica player, being closely observed by some of Europe's biggest clubs, will partner 34-year-old Cristiano Ronaldo in attack.
Otherwise, the side was largely as expected with Bernardo Silva likely to play just behind the front two and veteran Pepe at the heart of the defence.
Switzerland made three changes to the side which drew 3-3 against Denmark in March as Fabian Schaer, Xherdan Shaqiri and Haris Seferovic -- who plays his club football in Portugal with Benfica -- returned to the team.
News that makes sense
Your trusted source for staying up-to-date with the world around you. Get free daily news updates and analysis, straight to your inbox.
Teams:
Portugal: 1-Rui Patricio; 20-Nelson Semedo, 3-Pepe, 4-Ruben Dias, 5-Raphael Guerreiro; 14-William Carvalho, 18-Ruben Neves, 10-Bernardo Silva, 16-Bruno Fernandes; 23-Joao Felix, 7-Cristiano Ronaldo
Switzerland: 1-Yann Sommer; 2-Kevin Mbabu, 22-Fabian Schaer, 5-Manuel Akanji, 13-Ricardo Rodriguez; 10-Granit Xhaka, 8-Remo Freuler, 17-Denis Zakaria, 14-Steven Zuber; 23-Xherdan Shaqiri, 9-Haris Seferovic
(Reporting by Brian Homewood; Editing by Toby Davis)
