City started the match as favourites and blew Birmingham away in the first half with three goals inside the first 32 minutes in front of a record crowd for a women's FA Cup final.
First Lucy Bronze scored with a cute header in the 17th minute, Isobel Christiansen doubled the lead nine minutes later before Women's World Footballer of the Year Carli Lloyd nodded home a third after 32 minutes.
Birmingham City pulled a consolation goal back when substitute Charlie Wellings scored with a superb low strike in the 73rd minute but Jill Scott's 80th minute effort sealed the victory.
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(Reporting By Tom Hayward, editing by Pritha Sarkar)
