They all missed Scotland's opening three games of the championship, which have brought victories over France and England at home after defeat in Wales.
Coach Gregor Townsend has also called up loose forward John Hardie, who was suspended last year for alleged cocaine use, and uncapped 22-year-old scrumhalf George Horne, whose has scored 10 tries in 14 games for Glasgow Warriors this season.
Injuries rule out winger Tim Visser and flanker Rob Harley.
News that makes sense
Your trusted source for staying up-to-date with the world around you. Get free daily news updates and analysis, straight to your inbox.
The size of the squad has increased from 36 to 40 players for the last two games. After Saturday's clash in Dublin, Scotland complete the championship in Rome against Italy on March 17.
(Reporting by Mark Gleeson; Editing by Ed Osmond)
