The Westminster leader of the Scottish National Party says it would be an "outrage" if the UK government sought to return its Brexit deal to the House of Commons for a fourth time, and implied that Scotland may need to reconsider independence to secure its future as a European state.
Ian Blackford, whose SNP are Scotland's largest political party, added a "vast majority" of Scottish MPs had voted to revoke Article 50, which sends Britain out of the EU, as well as for a people's vote.
"It really is about time that the Government accepted reality. That the deal the Government put forward has been defeated three times with the largest defeat in parliamentary history," Blackford said.
"It is crystal clear to us in Scotland that our votes in this house are disrespected.
"It is becoming increasingly clear to the people of Scotland that if we want to secure our future as a European nation, then we are going to have to take our own responsibilities.
"The case is this - sovereignty rests with the people of Scotland, not with this house. The day is coming where we will determine our own future and it will be as an independent country."
Scotland previously voted against independence in a 2014 referendum, prior to the successful 2016 Brexit referendum.
Britain had been due to leave the EU on March 29 but the political deadlock in London forced May to ask the bloc for a delay. As things stand, Britain will now depart at 2200 GMT on April 12.