A specialised diet high in resistant starch found in many foods including fruit and vegetables provides "complete" protection against type 1 diabetes, according to a new study.
Research conducted at the Monash University's Biomedicine Discovery Institute found the diet developed by the CSIRO benefits the immune system because of the high amounts of short-chain fatty acids acetate and butyrate it produces within the gut.
"The Western diet affects our gut microbiota and the production of these short-chain fatty acids," researcher Dr Eliana Marino said.
"Our research found that eating a diet which encourages the gut bacteria that produce high levels of acetate or butyrate improves the integrity of the gut lining, which reduces pro-inflammatory factors and promote immune tolerance."
"We found this had an enormous impact on the development of type 1 diabetes."
The findings have been published in journal Nature Immunology.
Professor Charles Mackay, who initiated the research, says the study highlights how drug-free approaches including special diets could treat or prevent autoimmune diseases such as type 1 diabetes.
"The findings illustrate the dawn of a new era in treating human disease with medicinal foods," Professor Mackay said.
"The materials we used are something you can digest that is comprised of natural products - resistant starches are a normal part of our diet.
However, he says, the diet is not just about eating vegetables or high-fibre foods but involves special food and a special process, and would need to be managed by nutritionists, dietitians and clinicians.
FOODS HIGH IN RESISTANT STARCH: * Potato
* Cashew nuts
* Bananas
* Oats
* White beans
* Lentils
