"The days after, back in Barcelona, were the worst moments of my life and career along with the 2014 World Cup; I wanted to disappear from the world," Uruguay striker Suarez said in an interview with Fox Sports ahead of the Copa America.
"I didn't want to take my children to school, everyone could see I was in a very bad way. I had days I didn't want to do anything, they were very difficult moments."
The 4-3 aggregate defeat to Liverpool came a year after Barca also surrendered a three-goal advantage in a Champions League quarter-final tie by losing 3-0 to AS Roma and were knocked out on away goals.
Suarez, however, said he could not have imagined history repeating itself when his side turned up at Anfield last month knowing that if they scored once Liverpool would have to score five.
"I didn't see it because we are Barcelona and we thought we'd have two or three chances to score; we said this but we became nervous, we gave stupid passes away, we didn't show the right attitude," Suarez added.
"When the first goal came we didn't know how to react, we knew we had really messed up. After the game in the dressing room no-one could say anything; there was sadness, bitterness and disappointment because we knew we'd given an awful image."
Days after the defeat to Liverpool, Suarez opted to undergo surgery to treat a long-term knee problem in order to be fit for the Copa America, which begins on Friday with hosts Brazil taking on Bolivia.
Uruguay, who have won the tournament a record 15 times, play their first game against Ecuador on Sunday.
(Reporting by Richard Martin; editing by Clare Fallon)
