Thirty people arrested in a massive drug swoop around Melbourne and parts of Victoria will appear in Melbourne Magistrates Court on Wednesday.
Police arrested 43 people on Tuesday and of the remainder, nine people were charged and bailed, two were cautioned and two were released pending further inquiries.
Charges involve a range of drug-related offences including cultivating and trafficking commercial quantity of cannabis.
Police say they have smashed several international drug syndicates, with Vietnamese origins, that have raked in $400 million in drug money since Operation Entity began two years ago.
Almost 650 police officers and members of the Australian Federal Police, immigration department and other agencies pounced on 68 properties on Tuesday in what they described as the biggest day of drugs raids in Victorian history.

