Ms Trump underwent a surgical procedure on May 14 to treat a benign kidney condition and was released from the hospital on May 19.
The US first lady, who has not been seen in public since May 10, attended last year’s G7 summit in Italy.
“She will not attend the G7 and there are no plans for her to travel to Singapore at this time,” her spokeswoman, Stephanie Grisham, said in an e-mail on Sunday.

Melania Trump with France's First Lady Brigitte Trogneux during G7 Taormina summit on the island of Sicily in Taormina, Italy on May 27, 2017. Source: NurPhoto
Ms Trump tweeted on May 30 in response to news stories about her absence from public view.
“I see the media is working overtime speculating where I am & what I’m doing. Rest assured, I’m here at the @WhiteHouse w my family, feeling great, & working hard on behalf of children & the American people!” she wrote on Twitter.
A reporter for CNBC tweeted that he saw the first lady in the White House on May 29 with her aides.
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