Last December, Breazeale stopped Carlos Negron of Puerto Rico in the ninth round and is the WBC's mandatory challenger.
"It's always a great thing to get the mandatories out of the way because I consider the mandatories like flies -- they are always buzzing in your ear," Wilder, known as the Bronze Bomber, said at a media conference.
Breazeale, whose only loss was to WBA, IBF, WBO and IBO champion Anthony Joshua in 2016, added he was looking forward to try and silence his fellow 33-year-old.
"I'm excited to finally get this chump in the ring," he said. "You love your own voice. All you do is talk and talk and talk.
News that makes sense
Your trusted source for staying up-to-date with the world around you. Get free daily news updates and analysis, straight to your inbox.
"It's time to get into the ring and square off."
(Reporting by Rory Carroll; Editing by Greg Stutchbury)
