"Rolled my ankle during practice today, very sad to miss Fed Cup and Istanbul, but I'll be back soon," the 25-year-old Dane said on Twitter on Friday.
Wozniacki, now down at 24th in the rankings after a disappointing showing at Indian Wells and Miami, was scheduled to play for her country in the Fed Cup Group II seven team round-robin tournament next weekend in Cairo.
She won the Istanbul title in 2014.
(Reporting by Martyn Herman; Editing by John O'Brien)
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