Aiden Bonar will make his AFL debut amid more setbacks for the injury-plagued GWS.
Bonar, who was the Giants' first pick in last year's draft, has been called up to bolster his side's midfield in the absence of Dylan Shiel (ankle) and Tim Taranto (knee).
Coach Leon Cameron is upbeat Taranto and Sam Reid (knee) will only miss Sunday's clash with Carlton at Etihad Stadium, but Shiel could spend a couple of weeks on the sidelines.
The Giants' campaign was derailed by a stack of long-term injuries to key personnel during the first half of the season, which hit a low point when they suffered four defeats in a row.
Tom Scully, Zac Williams and Jon Patton headline the talent still on the sidelines, but the return of stars Josh Kelly, Toby Greene and Brett Deledio has helped power the expansion club's resurgence.
Cameron insists GWS, who have won seven of their past eight games to be on the cusp of the top four, aren't using a clash with the wooden spoon favourites to rest some of their prime movers.
Shiel's problem is the biggest concern.
"He rolled his ankle a few weeks ago and we've been playing catch up. He rolled it again on the weekend," Cameron said.
"He didn't complete training ... it will be touch and go for next week.
"There is clearly ligament (damage), so that is a time thing really. We wanted him to play desperately, like Tim and Reidy.
"It's disappointing."
The positive injury news for the Giants is that Jeremy Cameron returns fitter from a five-game suspension.
Cameron, who was restricted by a toe issue earlier this year and suffered multiple hamstring strains at the pointy end of their 2017 campaign, has done a mini pre-season during his long stint on the sidelines.
"He's covered a lot of miles, done a lot of cross training, footy training," Leon Cameron said of his namesake.
"I'm a little bit excited and a little bit nervous, because creating the synergy and cohesion (in the forward line) takes a few games."
"Better decision making, coming into big collisions, is going to be his challenge. I'm really confident he's taken that on board."
Cameron expected the big-bodied Bonar to hit the Blues' midfield hard.
"You'll know you've been tackled by him," he said.
"He loves to tackle and put his head over the footy."
