Australia will target English captain Charlotte Edwards and fellow batter Arran Brindle as the host nation tries to fight its way back into Ashes contention.
England's 61-run Test win in Perth earlier this week means they have control of the cricket series ahead of the limited-overs games.
Under the multi-format program used for the women's Ashes, England gained six points for winning the only Test of the series.
The remaining three one dayers and three T20 matches are worth a total of 12 points.
Ahead of the first one-dayer at the MCG this Sunday, Australian pace bowler Holly Ferling said they must ramp up the pressure on Edwards and Brindle.
"We're looking forward to Sunday, when we can rip into the Poms again," she said.
"Charlotte Edwards is definitely one who will keep a partnership going.
"For us, she's a major, major wicket.
"Also being the captain and having the energy around her, we need to make sure that we can cut that off."
Brindle top-scored in the first innings with 68 at the WACA and Edwards' 56 was the only half-century of their second dig.
But Brindle scored at a slow rate in the Test and Ferling wonders how she will perform in the shorter format.
"She did really well in the Test, but coming into the one dayers she might struggle with trying to keep the run rate up," Ferling said.
"If we can 'dot up' Lottie and Arron, I'm pretty sure we should be on top of them."
Ferling said after the pace-friendly WACA, the two teams might bring in a second spin bowler for the MCG.
Australia's Erin Osborne was the only spinner to take a wicket in the Test and Ferling said she would have a crucial role during the one dayers.
"She really does hold her own against the batters and dries up an end," Ferling said.
"That's her main role in the team and if she's able to execute that, hopefully wickets fall at the other end."
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