Ivory Coast take on Mali at the Nuevo Estadio de Malabo before Cameroon meet Guinea at the same venue.
The first two group matches ended 1-1 with Cameroon coming from behind against Mali and the Ivorians, despite being down to 10 men, holding Guinea.
Striker Gervinho will be missing for the Elephants as he starts a two-match ban for the red card he received for retaliation against Guinea.
Captain Stephane Mbia returns for Cameroon after completing a suspension picked up in qualifying but his deputy Enoh Eyong is still out with injury.
On Friday, Senegal went top of Group C after a 1-1 draw with South Africa while Ghana beat Algeria 1-0 thanks to a late goal from Asamoah Gyan.
(Editing by Tony Jimenez; mark.gleeson@thomsonreuters.com; +240222770533; Reuters Messaging: mark.gleeson.thomsonreuters.com@reuters.net)
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