Colombian David Ospina was selected in Paris and made some fine saves but manager Arsene Wenger told a news conference on Friday that Cech would be back at Hull.
He added that Wales midfielder Aaron Ramsey was still unfit and would also miss the League Cup game at second-tier Nottingham Forest on Tuesday.
"We are cautious with him, we do not want a setback with his hamstring," Wenger said.
Striker Olivier Giroud, sent off after going on from the bench in Paris, is doubtful because of a toe injury.
Swiss midfielder Granit Xhaka was also a substitute in midweek but Wenger has tipped him to "have a huge impact" at the club.
"Xhaka is adapting to the pace of the English game...he has the engine power, a long pass and likes to come deep," said the Frenchman.
Wenger, who celebrates 20 years at Arsenal next week, was complimentary about Hull's interim manager Mike Phelan.
"He's done really well," said Wenger. "He's a real football man who's given some stability to Hull who are difficult to beat."
(Reporting by Steve Tongue; Editing by Tony Jimenez)
