Table-topper City sit marginally above United on goal difference after both sides won their first three league games.
"It's going to be a very beautiful game. The two teams arrive to this game having taken good results and after making wholesale changes in every sense," the 30-year-old told Spanish radio station Cope.
"We've started the season very well and it should be a great game. But we won't be playing for a draw. We will go out to win the match."
City have won three times and drew one in their last five top flight meetings with United at Old Trafford.
"It's a ground where in the last few years things have gone okay for us. We know they are a very difficult rival - but we won't settle for a draw," Silva added.
(Reporting by Ian Rodricks in Bengaluru; editing by Amlan Chakraborty)
