Clot-busting drug helps stroke victims

Patients given a clot-dissolving drug within hours of suffering a stroke have a better and faster recovery.

Stroke patients who are given a clot-busting drug soon after an attack have a better and faster recovery, new research suggests.

The study of more than 6750 stroke patients by a team of Australian and international scientists, published in The Lancet, found patients who received the drug alteplase within three hours of an ischaemic stroke - the most common form - were 75 per cent more likely to have no major disability six months later, compared with patients who did not receive the drug.

"Alteplase is effective in dissolving blood clots in those who have suffered a stroke, and is particularly effective if it is administered within three hours," the authors wrote.

Every year, about 55,000 Australians suffer a stroke, which occurs when the blood supply to the brain is restricted due to a blockage or bleeding.

About 65 per cent of those who survive a stroke suffer a disability that prevents them living their lives without assistance.

Previously, doctors have been wary of using alteplase because it increases the risk of a fatal brain haemorrhage in the first few days after treatment.

But study co-author Professor Richard Lindley, of the University of Sydney, said the benefits outweighed the risks.

"This treatment is not without its risks; however, the risks are worth the benefits, given that stroke is so disabling.

"Our data revealed that the benefits of alteplase occurred despite an increase in the number of early fatal intracranial haemorrhages of about two per cent."

National Stroke Foundation chief executive Dr Erin Lalor said the study emphasised that time was critical when treating stroke.

"Often people may ignore the symptoms or wait too long to seek medical attention, thinking it will be all right, particularly as symptoms may only appear for a short period of time," Dr Lalor said.

"When the blood supply to the brain is stopped, the brain cannot get the food and oxygen it needs and starts to die.

"When this happens, it sets off a chain reaction, spreading the damage to more of the brain.

"The sooner this treatment is given, the better the chances of a good recovery."

HOW DO YOU KNOW IF SOMEONE IS HAVING A STROKE? THINK F.A.S.T.

Face - Has the person's mouth drooped?

Arms - Can they lift both arms?

Speech - Is their speech slurred? Do they understand you?

Time - Time is critical.

If you see any of these signs, call triple-zero (000).


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