Tinkoff-Saxo rider Contador crashed near the finish of Sunday's Tour of Lombardy, allowing second-place finisher Valverde to leapfrog his rival in the standings with one WorldTour event left, the Tour of Beijing starting on Friday.
"Bad news. Training today, hardly could pedal because of the knee, finally I don't go to China. Next thing is to do an MRI and start thinking of 2015," Contador wrote on his Twitter feed on Monday.
Valverde, who finished fourth overall in the Tour de France and third in the Vuelta, has 686 points in the WorldTour rankings to Contador's 620.
Australia's Simon Gerrans is third on 478 points but cannot overhaul the Spaniards.
(Reporting by Julien Pretot; Editing by John O'Brien)
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