West Indies lost both openers lbw, Leon Johnson falling to fast bowler Rahat Ali for 12 and Darren Bravo to spinner Yasir Shah for 43.
Kraigg Brathwaite and Marlon Samuels shared a steady third-wicket partnership of 41 but both fell in quick succession shortly before the close to give Pakistan the upper hand.
Samuels was caught by Sami Aslam at slip off Rahat for 30 and two balls later Brathwaite was needlessly run out for 21 following a mix-up with his partner Devendra Bishoo.
(Reporting by Ed Osmond; editing by Martyn Herman)
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