England lead the series 1-0 after a thrilling 31-run victory at Edgbaston.
Steady rain forced the covers to be on all day and although a spell of dry weather in mid-afternoon raised hopes of some play, the bad weather returned to ensure a frustrating day for both teams.
There has been no toss and neither side has named a team.
Twenty-year-old batsman Ollie Pope is expected to be given his England debut at number four after replacing Dawid Malan in the squad.
Thursday was the first time a full day's play has been lost at Lord's since the opening day of the first test against Pakistan in 2001.
(Reporting by Martyn Herman, Editing by William Maclean and Pritha Sarkar)
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