Adelaide will recall out-of-favour veteran Bryce Gibbs and give Ben Davis his AFL debut in the Friday night blockbuster against Geelong.
The Crows dropped Gibbs in round 11, while Davis is finally in the senior team after being recruited with the No.75 pick in the 2016 national draft.
Elliott Himmelburg is also back for Adelaide as Wayne Milera (back), Josh Jenkins (knee) and Cam Ellis-Yolmen (shin) miss through injury.
The Cats made two changes, losing Gary Rohan to concussion and dropping Darcy Fort.
Lachie Fogarty and Jed Bews will take their places.
With three-straight wins that included victories over GWS and Richmond, the Crows are back in the top-four hunt.
Geelong remain a game clear at the top of the ladder, but lost again coming out of their mid-season bye last weekend against Port Adelaide.
Veteran Cats defender Zach Tuohy said the loss was a bigger deal outside the club, because Geelong already knew their deficiencies well.
"We were fully aware of what we were doing well and not doing well," Tuohy said.
"We played games earlier this year that but for a surge late or a couple of players' excellence, we probably would have lost.
"So we were under no illusions that we weren't playing nearly as good as we could have played, even when we were winning.
"We need to improve a lot if we want to go where we want."
Tuohy also made it clear the Port loss had not dented Geelong's confidence.
"We're more disappointed with it in isolation," he said.
"But in the bigger picture, we play anything near our best, we're going to beat nearly anyone, probably anyone in the league.
"So it's not a big deal."
Geelong beat Adelaide away earlier this season, but Tuohy has no doubts about the Crows' ability to return the favour.
"This will be a big test, because they'll be there when the whips are cracking," he said.
One of the biggest tests for Tuohy and his fellow defenders will be freakish Crows small forward Eddie Betts.
The Cats backman has played on Betts several times and knows all too well the dangers involved.
"Eddie's one of those types that you can keep him quiet for 90 per cent and then he'll kick two from the pocket with five blokes hanging off him," Tuohy said.
"He's kind of unstoppable because you think you have him stopped and he'll still do something ridiculous."
