CSIRO boss Larry Marshall will front a Senate inquiry one day after announcing 275 science jobs will be slashed from the government's peak science body.
In an email to workers on Tuesday, Dr Marshall advised that CSIRO will employ 40 full-time scientists at a new centre in Hobart as part of a decade-long commitment.
The number of job losses is down from the 350 announced in February's proposed restructure of the agency's 5000-strong workforce.
Dr Marshall will be quizzed about the CSIRO's latest moves when he appears before a Senate committee scrutinising the federal government's budget measures in Canberra on Wednesday.
CSIRO's chief financial officer Hazel Bennett and environment department director Alex Wonhas will also appear.
A separate Senate inquiry into the outcomes of the last Council of Australian Governments meeting, where Prime Minister Malcolm Turnbull handed the states and territories an extra $2.9 billion for hospitals, will also hold a public hearing in Canberra on Wednesday.
Officials from the department of prime minister and cabinet will appear, while the head of the Australian Medical Association Brian Owler will also be quizzed.