North Melbourne has called on midfielder Nick Dal Santo for the first time in ten rounds with the midfielder finally overcoming a hamstring strain.
Not since round two has Dal Santo appeared for the Kangaroos after requiring surgery on his hamstring.
But after positive noises from Kangaroos interim boss Darren Crocker during the week, the 31-year-old has been recalled, along with Shaun Atley, to face a shaken-up GWS Giants side.
Ryan Bastinac and Shaun McMahon make way for the returning duo, but North Melbourne's two changes have nothing on the six made by the Giants.
Will Hoskin-Elliot and James Stewart have been dropped, joining the injured foursome of co-captain Phil Davis, Shane Mumford, Joel Patfull and Stephen Coniglio on the sidelines.
Caleb Marchbank and Jack Steele will debut for the young Giants side, which could drop to eighth if they lose to the Kangaroos.
After Richmond enjoyed a week off celebrating their fine win over previously unbeaten Fremantle in Perth, the Tigers will take on West Coast with an unchanged line-up.
Richmond assistant coach Brendon Lade said being able to name the same 22 made the Tigers coaching group a happy bunch.
"It's been a long time coming," he told the club's website.
"We took a lot of confidence out of last week and hopefully we can take that into West Coast this week."
The Eagles named Matt Rosa for the first time since round four, but opted against recalling Jeremy McGovern, giving the talented defender a two-week break from a thigh strain.
Carlton caretaker John Barker has shown his forgiving side, recalling Chris Yarran after his internal ban for repeated lateness.
Yarran and Bryce Gibbs come into the Blues team for retired legend Chris Judd and Jason Tutt respectively for their battle with Port Adelaide.
Power coach Ken Hinkley has made his frustration with his side known at selection, axing Tom Clurey, Sam Gray and Aaron Young.
Jackson Trengove has overcome an ankle injury and joins Kane Mitchell as one of five new faces for Port Adelaide.
Both Western Bulldogs and Brisbane Lions have been able to recall key names ahead of their meeting at Etihad Stadium on Saturday night.
Marcus Bontempelli and Liam Picken, who signed a two-year extension with the Bulldogs this week, return for the first time since round nine at the expense of Stewart Crameri (ankle) and Lin Jong (omitted).
For the Lions, Jed Adcock (calf) Jack Redden (back) and Daniel McStay (finger) return, adding 330 games of experience into Brisbane's line-up.
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