"I have achieved what I dreamed of as a seven-year-old running around and playing football in Ryomgaard," the 39-year-old Jorgensen said in a statement announcing his retirement on his club's website.
"I have been fortunate and privileged to play at the highest level with and against many talented footballers."
He has played over 100 games since returning to Aarhus from Italy in 2010 aged 34 to close out his career.
Capped 102 times, Jorgensen played at three World Cups and two European championships, scoring 12 goals including the opener against Brazil in a 3-2 quarter-final loss at the 1998 World Cup.
(Reporting by Philip O'Connor; Editing by Ken Ferris)
