The remains of the missing Beaumont children have not been found in an Adelaide excavation but police have vowed to never give up trying to solve Australia's most baffling cold case.
Information provided by two people in July this year sparked the latest inquiries, which ultimately centred on a factory site at suburban North Plympton.
The area was checked with ground-penetrating radar which indicated possible objects within the soil.
But when a three-metre hole was dug on Wednesday, nothing was found.
Police Assistant Commissioner Paul Dickson said the latest line of inquiry was now at an end but the Beaumont case would never be closed until it was successfully resolved.
"We were all hoping for a breakthrough today, there's no doubt about that," Mr Dickson said.
"What we want is to resolve this investigation."
The Beaumonts, Jane, who was nine, Arnna, 7, and four-year-old Grant went missing on Australia Day, 1966 after failing to return from a trip to Glenelg beach.
Investigations to uncover their fate over the past 47 years have extended across the country and to New Zealand while a Dutch clairvoyant became involved at one stage but failed to solve the mystery.
Mr Dickson said there was no doubt that as more years passed, the chances of cracking the case diminished.
"That's just common sense," he said.
"But we only need one or two pieces of information that will resolve the jigsaw.
"We will always look for those bits of information.
"Every case can be solved. All we need is that integral bit of information to get there."
During Wednesday's excavation police also had victim contact officers with members of the Beaumont family to offer support and to keep them informed.
"They have been kept fully abreast of the investigation at all times," Mr Dickson said.
"Unfortunately this is a very long and involved investigation and it does give a lot of hurt and pain to the family.
"What we try and do, as best we can, is to be with the family to try to mitigate that."
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