Sixth seed Juan Martin del Potro overcame a slow start to beat German Philipp Kohlschreiber 3-6 6-3 7-6(4).
Kohlschreiber, ranked number 23 in the world, served 22 aces and hit 50 winners against a sluggish del Potro. But the Argentine, who said he had been feeling ill, fought back to get an early break in the second set and get a grip on the match.
"It was really tough for me," del Potro, who later withdrew from doubles, told reporters. "I couldn't run a lot. I think my serve helped me a lot to keep playing for the three sets because I made many aces.
"With my serve I didn't run too much. I was lucky in the tie-break because he made a few mistakes. I won a really tough match."
France's Jo-Wilfried Tsonga had a much easier start to his campaign as he brushed aside Pablo Andujar 6-3 6-2 in 65 minutes.
Tomas Berdych of Czech Republic, currently sixth in the race for next month's ATP World finale in London, also took a positive step towards sealing his berth by defeating Spain's Feliciano Lopez 7-6(5) 6-2.
(Writing by Sudipto Ganguly)
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