Bowlers can deliver either five or 10 consecutive balls, with each bowler allowed a maximum of 20 deliveries per game.
"The Hundred will help cricket to reach more people," ECB Chief Executive Tom Harrison said, after first-class counties had voted 17-1 in favour of the playing conditions.
The new competition, aimed at attracting a wider audience to cricket, will also feature a 25-ball powerplay start for each team, with each bowling side allowed to take a strategic timeout of up to 2-1/2 minutes.
"We remain totally committed to the existing, popular forms of cricket and will be committing significant funds and focus to all levels of the game, protecting and nurturing the core whilst reaching out to a wider audience."
The identities of the eight teams involved in the first edition of the tournament will be agreed later this year, with a player draft scheduled for the autumn.
(Reporting by Simon Jennings in Bengaluru, editing by Pritha Sarkar)
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