Giant wing Joe Cokanasiga will be given the chance justify coach Eddie Jones' belief he is "something special" when he makes his England debut against Japan.
The Bath back is one of 11 changes in personnel for Saturday's International at Twickenham with only fullback Elliot Daly retaining the same jersey he wore against New Zealand.
Flyhalf George Ford leads the team after co-captains Owen Farrell and Dylan Hartley were selected on the bench in a match and its build-up being treated as a dress rehearsal for the four-day turnaround between group games against Tonga and the USA at next year's World Cup.
It is the presence of Cokanasiga that is generating most excitement, however, as Jones tests whether he can perform the role of juggernaut wing that England have rarely been able to field.
The giant Fijian-born threequarter has used his frame to destructive effect this season and Jones believes he has the attributes to be a force in the international arena.
"Joe's pretty excited. He's a quite a shy boy but increasingly, in the time that he's spent with the team, he's come out of himself," former Wallabies coach Jones said.
"There's something a little bit special about him so we're looking forward to seeing him play.
"He's got power and he's got pace. The Japanese wingers are very good wingers so he'll have to be at his best."
Jones is preparing to face the team he coached to rugby's greatest upset when South Africa were stunned in Brighton at the 2015 World Cup.
"Japan are progressing really nicely. The team has regenerated - there are only five or six players left from the team that I coached and they're the outstanding players like Michael Leitch and Kenki Fukuoka," Australian mentor Jones said.
"Those guys are still there but they've brought some good players in. And I think Japan are benefiting from playing Super Rugby.
"Previously Japanese sides were happy to get beaten, they were the Brave Blossoms, but now this new generation of Japanese players believe that they can win and that makes them a much stronger team."
Leitch leads a Japan team showing eight changes for the Twickenham encounter.
Japan were thumped 69-31 by New Zealand on November 3 and head coach Jamie Joseph has revealed some of the changes were enforced.
"It's the best team that's available. We have some injuries back at home which haven't helped, but I'm confident in terms of the way we prepare," Joseph said.
