Former Speaker Peter Slipper will contest the federal election.
The independent member for Fisher says he will recontest his Queensland seat next month.
"It is a David and Goliath effort, every election is a challenge," he told reporters outside his Sunshine Coast electorate office on Thursday.
"You can't take the support of people for granted, I never have."
Mr Slipper made the announcement one hour after nominations for candidates closed at noon (AEST) on Thursday.
He will be running against former Howard government minister and Liberal National Party candidate Mal Brough.
Mr Slipper served as the Speaker of the House of Representatives from November 2011 to October 2012, when he resigned amid allegations of fraud and sexual harassment by former staffer James Ashby.
The sexual harassment case was thrown out by Federal Court Justice Stephen Rares, who found Mr Ashby's predominant purpose for bringing the case was to pursue a political attack against his former boss.
However, Mr Slipper is due to face trial in December over the alleged misuse of Cabcharge dockets.
He has pleaded not guilty to the charges.
Mr Slipper said the last 18 months had been extremely difficult for his family, but he was optimistic about his chances of holding on to his seat.
"I'm very confident to be judged by the people of Fisher," he said.
"The messages that I get back from the community, particularly since the Justice Rares decision, is that people have seen through the plot that was set up against me."
Mr Slipper was coy when asked who he would direct his preferences to.
"One doesn't decide what happens with preferences until nominations close. They have closed, but of course those who have nominated will not be announced until tomorrow," he said.
"I'll be making the appropriate decisions at the appropriate time."
