Team Sky rider Froome hit the deck with about 30km left but got back on his bike with the right side of his shorts torn, helped by team mates Michal Kwiatkowski, Mikel Nieve and Christian Knees.
Another main contender, France's Romain Bardet, was also involved in the pile-up.
After a brief chase with other riders caught up in the crash, which happened when a rider hit the ground at the front of the peloton, Bardet and Froome made it back to the main pack.
(Reporting by Julien Pretot; Editing by Clare Fallon)
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