Compounding the strongman's woes, a security services building and the headquarters of Libya's anti-corruption agency were on fire in Tripoli early Tuesday after apparently being hit by NATO air strikes.
In The Hague, ICC chief prosecutor Luis Moreno-Ocampo applied on Monday for warrants for the arrest of Gaddafi, his son Seif al-Islam and intelligence head Abdullah Senussi for crimes against humanity.
The Argentine prosecutor said there was evidence "that Moamer Gaddafi personally ordered attacks on innocent Libyan civilians."
A panel of ICC judges will now decide whether to accept or reject the prosecutor's application.
Moreno-Ocampo said thousands of people had been killed and around 750,000 people forced to flee since Gaddafi ordered his forces to crush protests against his four-decade autocratic rule that began on February 15.
The two buildings hit on Al-Jumhuriya Avenue are close to the residence of strongman Moamer Gaddafi in an area where two explosions were heard around 1.30am on Monday.
By 3.00 am firefighters were battling to control flames that were tearing through the two facing buildings, said an AFP correspondent who was with a group of international journalists
brought to the area by Libyan authorities.
The head of Libya's Ministry for Inspection and Popular Control, the anti-corruption agency, was at the scene and said that some ministry employees had been injured, but provided no further
details.
Government spokesman Mussa Ibrahim later said that the rebel National Transitional Council (NTC) had directed NATO to attack the agency in a bid to destroy files related to former regime officials
who have joined the rebellion.
"We believe that NATO has been misled to destroy files on their corruption cases," he told journalists.
Parts of Tripoli have been targeted almost daily by NATO-led strikes launched on March 19 after a UN resolution called for the protection of civilians from Gaddafi's government.
