The South American pair have faced criticism for their performances this season after Guardiola sent his previous first-choice keeper, England international Joe Hart, on loan to Torino.
Guardiola has rotated Bravo and Caballero but the former is again under the spotlight after conceding a soft goal in last weekend's 3-1 victory over Hull City.
"Last week I decided for Claudio; what I see in the training session is what counts," said Guardiola at a news conference on Thursday ahead of Saturday's game.
"Every weekend I will decide who will play in goal," said Guardiola, repeating that he will address Hart's future at the end of the season.
City's manager refused to answer questions on Bravo's Chilean team mate, Arsenal's Alexis Sanchez, who has been consistently linked in the British media with a summer move to City.
"It is not time to talk about that," said Guardiola. "Not time to talk about the players who will stay here. We have a lot of business to do."
Vincent Kompany is fit for the trip to Southampton but Willy Sagnol (abductor) is again absent.
(Reporting by Neil Robinson Editing by Jeremy Gaunt)
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