"Bitter blow for Hamburg as the captain has suffered a muscle fibre tear," the club said.
The 28-year-old Switzerland defender scored an 89th-minute goal to help his team claim their first victory of the season against Stuttgart.
Hamburg, who needed a relegation playoff for the second consecutive year last season to stay up, take on Cologne on Saturday.
(Reporting by Karolos Grohmann, editing by Tony Jimenez)
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