British businessman Shrien Dewani has finally been extradited to stand trial for allegedly murdering his wife during a staged car-jacking on their 2010 honeymoon in South Africa, police say.
Officers from Britain's Metropolitan Police Service (MPS) Extradition Unit took Dewani, 34, from Fromeside Hospital in south west England, where he has been receiving treatment for reported mental health problems, to nearby Bristol Airport.
There he was handed over to representatives from the South African authorities, who escorted him onto a plane that took off on Monday night, according to a Scotland Yard statement.
Dewani denies ordering the killing of his 28-year-old Swedish bride Anni in Cape Town in November 2010, and has been fighting extradition from Britain ever since.
He claimed he had mental health problems, including depression and post-traumatic stress, and was detained under mental health legislation.
But a British court ruled last month that after numerous legal challenges, he could be sent to South Africa.
Dewani is due to land in Cape Town on Tuesday morning, where he will be taken directly to the Western Cape High Court to be formally charged.
He will be accompanied on the flight by a doctor, a nurse and police officers, the South African justice ministry said, given that he is "currently a patient and suspect who is in police custody and may need medical assistance en-route".
Dewani claimed he and his bride were kidnapped at gunpoint as they drove through the Gugulethu township near Cape Town in a taxi.
South African Xolile Mngeni was jailed for life for the murder in December 2012. Two other men jailed over the killing allege that Dewani ordered the hit.