"Is India going to happen next year? Probably not," he said at the Hungarian Grand Prix.
Asked what the problem was with the race at Greater Noida, near New Delhi, the 82-year-old British billionaire replied: "Very political."
Ecclestone, who has run Formula One for decades, draws up the calendar and usually presents it to the governing International Automobile Federation to be rubber-stamped in September.
He currently has a possible 22 races jostling for space on the calendar with teams expressing a strong preference for a maximum of 20.
Russia, with a debut race pencilled in for the Black Sea resort of Sochi towards the end of next year, and a grand prix in New Jersey are the two novelties planned for 2014 with Austria also due to make a comeback after an 11-year absence.
India first hosted a grand prix in 2011 to positive reviews from the Formula One community and this year's is scheduled for October 27 as the 16th round of the 19-race championship.
The two races to date in India have both been won by Red Bull's triple world champion Sebastian Vettel.
There have been bureaucratic hurdles to overcome, however, as well as concern about finances and the sport's exposure to high local taxation.
Promoters Jaypee Sports International, which last month slammed the media speculation about next year's race as "totally baseless and malicious", hoped things will be sorted out.
"We have not got anything in writing from the Formula One management regarding the status of the 2014 Indian Grand Prix," Jaypee spokesman Askari Zaidi said by phone.
"We are keen that Formula One races take place in India at the Buddh International Circuit (BIC) till our contract is in operation that is 2015."
Next year's Indian Grand Prix was the subject of much discussion in Hungary, with teams recognising it faced problems but hoping they could be resolved.
"It would be a pity if for these (tax) reasons we don't go there," Sauber's Indian-born principal Monisha Kaltenborn told Reuters.
"India is an important market for partners who are already in Formula One or who could get into Formula One because of that market so it really would be a pity if we would not manage to sort out these problems."
(Additional reporting by Sudipto Ganguly in Mumbai; editing by Patrick Johnston)
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