Krul, who is the back-up goalkeeper in the Dutch squad, hurt his elbow on Saturday and has been replaced for the trip to Reykjavik by Feyenoord's Kenneth Vermeer.
Wijnaldum, who has hurt his knee, is not being replaced.
The Dutch beat Kazakhstan 3-1 in Amsterdam on Friday to pick up their first points in Group A.
(Reporting by Mark Gleeson; Editing by John O'Brien)
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