Israeli forces have launched a manhunt for attackers who killed three people in the central city of Elad as the country marked the anniversary of its founding, in the latest incident of deadly violence.
The search, backed by a large deployment of security personnel, helicopters, drones and roadblocks, was seeking what police described as "one or two terrorists", who remained at large hours after the attack on Thursday.
No details on the alleged assailants had emerged, but Defence Minister Benny Gantz announced measures to stop the suspects from "escaping and travelling" to the occupied West Bank, comments that pointed to possible Palestinian suspects.
The Magen David Adom emergency response service, which confirmed the deaths, said four others were wounded after the incident, which follows a series of fatal attacks committed by Palestinians and Israeli Arabs in recent weeks.
"We will get our hands on the terrorists... and ensure they pay the price," Prime Minister Naftali Bennett in a statement.
Specifics on how the violence unfolded remained unclear, but several Israeli media reports said the assailants carried knives, or an axe.
Other reports suggested the attackers had used firearms.
Israeli forces launched a manhunt for attackers who killed three people in the central city of Elad. Source: AAP, EPA / Atef Safadi
Israel's Foreign Minister Yair Lapid said "the joy of independence day had been interrupted in an instant," condemning the "murderous attack in Elad."
MDA paramedic Alon Rizkan, a first responder, described it as a "complex scene," identifying all of the dead as men in their early 40s.
The majority of Elad's 50,000 residents are members of Israel's ultra-Orthodox Jewish community, known as haredim, hundreds of whom had gathered at the attack site, wearing crisp white shirts amid a swarm of medical personnel and police.
Another majority Haredi city, Bnei Brak, which also lies on the outskirts of the coastal city of Tel Aviv, was targeted in March.
It was one of the areas hit in the string of attacks since 22 March that, prior to Thursday's incident, had killed 15 people including an Arab-Israeli police officer and two Ukrainians, in separate attacks inside Israel.
Two of the deadly attacks were carried out in the Tel Aviv area by Palestinians.
A total of 27 Palestinians and three Israeli Arabs have died during the same period, among them perpetrators of attacks and those killed by Israeli security forces in West Bank operations.
Specifics on how the violence unfolded remained unclear, but several Israeli media reports said the assailants carried knives, or an axe. Source: Getty, Anadolu / Anadolu Agency/Anadolu Agency via Getty Images
Palestinian territories president Mahmoud Abbas condemned "the killing of Israeli civilians" in Elad, warning it could lead to spiralling violence.
But Hamas Islamists, who control the Israeli-blockaded Gaza strip, and Islamic Jihad, another Palestinian armed group, praised the Elad attack, calling it a consequence of unrest at Jerusalem's Al-Aqsa Mosque compound.
Neither group claimed responsibility.
"This operation demonstrates our people's anger at the occupation's attacks on holy sites," Hamas spokesman Hazem Qassem said of the Elad attack.
"The storming of the Al-Aqsa Mosque cannot go unpunished."
Fresh clashes broke out earlier Thursday at Al-Aqsa, which is also the holiest site in Judaism, in which it is known as the Temple Mount.
The latest morning violence at the flashpoint site came following a tense April, in which nearly 300 people were injured in clashes between police and Palestinians at Al-Aqsa.
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