Uno, skating to a tango, won with 279.34 points despite a late fall in his routine while Americans Jason Brown and Adam Rippon placed second and third, respectively.
The bronze medallist in last season Grand Prix final became the fourth Japanese men's winner in the last five Skate Americas and youngest since France's Brian Joubert in 2002.
(Reporting by Larry Fine in New York, Editing by Andrew Both)
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