After an aerial assault on IS targets by US and Turkish fighter jets, the ground offensive began.
At dawn tanks crossed the border, followed by pick-up trucks believed to be carrying hundreds of fighters from Turkish-backed factions of the rebel Free Syrian Army.
Within hours, several of the factions involved announced they had liberated Jarablus from IS fighters.
"God has blessed us with freeing Jarablus since yesterday, and we won't stop working to free this country from the tyranny of IS forever, and eliminate them from Syria."
In Turkey's capital, Ankara, Turkish President Recep Tayyip Erdogan announced that the operation was a success.
"As of this moment, Free Syrian Army and residents of Jarablus have taken back Jarablus. They seized the state buildings and official institution buildings in the town. According to the information we just received, Daesh had to leave Jarablus."
President Erdogan was speaking with US Vice President Joe Biden, who was visiting Turkey as the Obama administration tries to smooth over thorny relations after last month's failed coup.
"We believe very strongly that the Turkish border must be controlled by Turkey, that there should be no occupation of that border by any group whatsoever other than a Syria that must be whole and united but not carved in little pieces. And we hope to continue to work with Turkey closely on continued operations that will root out Daesh and we're supportive of the operation."
Mr Biden has been working to reset strained relations with Turkey.
The United States sees the Syrian Kurdish YPG as an effective force against IS militants.
But Turkey believes they are linked to Turkish Kurds who have been fighting a three decades-long insurgency inside Turkey.
Turkey's assault on Jarablus was partly to ensure that the YPG makes no further gains in northern Syria, which it fears could extend Kurdish control along Turkish borders and fuel the ambitions of its own Kurdish seperatists.
Turkey has demanded that the YPG retreat to the east side of the Euphrates river within a week.
For now, Jarablus appears stable.
In the Turkish town of Karkamis, near Jarablus, the mayor, Nuh [noh] Kocaaslan, says he sees little chance of IS returning.
"We are carrying out controlled explosions to clear the mines planted by IS. After they are cleared, hopefully good days are ahead of us. As mayor, I had a lot of trouble because of IS. The lifeblood of my town was cut with their arrival."
Turkish troops say they will remain in northern Syria until Kurdish fighters withdraw completely.
At least 10 more tanks have moved across the border into Syria since the Jarablus operation.
It's unclear, though, if the deployment of the new tanks is aimed at securing the town, or helping the rebels move into new territory.
