Yamaha's Lorenzo swept around the circuit in one minute 53.471 seconds to top the timesheets ahead of Spanish compatriot Marc Marquez, who could seal the title in his rookie season on Sunday if he outscores the champion by eight points.
American Nicky Hayden rounded out the front row on his Ducati with Marquez's Honda team mate Dani Pedrosa, the winner of the race for the last two years, relegated to the second row in fourth place.
Friday's entire practice programme was wiped out by fog and wet weather, the latter also forcing the cancellation of Saturday morning's free practice session and leading to the extended 75-minute qualifying session.
(Writing by Nick Mulvenney; Editing by John O'Brien)
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