In an interview with Showtime to be broadcast on Saturday, Mayweather expressed his disgust that Pacquiao had blamed an injured right shoulder for his defeat by the American in the so-called "Fight of the Century" in Las Vegas.
Pacquiao, the former eight-division world champion, lost a unanimous decision to Mayweather on Saturday in the richest prize fight ever before undergoing successful arthroscopic surgery on his right shoulder four days later.
"I'm not going to buy into the bull--- ... and I don't want the public to buy into the bull----," Mayweather said in a sampling of quotes released by Showtime on Thursday.
"He lost. He knows he lost. I lost a lot of respect for him after all of this."
Asked by Showtime whether he had noticed Pacquiao being hampered by his shoulder during their 12-round bout at the MGM Grand Garden Arena, Mayweather replied: "Absolutely not."
He then added: "He was fast. His left hand was fast. His right hand was fast and he was throwing them both fast and strong. Excuses, excuses."
Barely one hour after the contest ended, Pacquiao's promoter, Bob Arum, said the 36-year-old southpaw had been troubled by a previous injury to his right shoulder.
"You guys saw the fight yourself. When you review the film, you'll see how infrequently he threw the right," Arum told reporters.
On Monday, an MRI scan in Los Angeles confirmed the Filipino had a torn rotator cuff and on Wednesday he underwent surgery.
INITIAL WILLINGNESS ABOUT RE-MATCH
Earlier this week, Mayweather said he would be willing to give Pacquiao a rematch next year, telling ESPN's Stephen A. Smith that he would delay his proposed retirement from the sport.
"I will fight him in a year after his surgery," Mayweather told Smith in a text.
Mayweather has one fight remaining on his Showtime contract and has repeatedly said he intends to quit after a bout in September, although after Saturday's fight he told reporters that he is "human" and occasionally contradicts himself.
On Thursday, however, the 38-year-old American made a complete U-turn on that statement.
"Did I text Stephen A. Smith and say I will fight him again? Yeah, but I change my mind," said Mayweather.
"At this particular time, no, because he's a sore loser and he's a coward ... If you lost, accept the loss and say, 'Mayweather, you were the better fighter'."
(Editing by Andrew Both)
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